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Associate Professor 


Education background

Sep, 2003-Jun, 2009, Chinese Academy of Agricultural Sciences (CAAS)

Ph.D. of Science, biochemistry and molecular biology, Biotechnology Research Institute

Sep, 1999-Jul, 2003, Inner Mongolia Agricultural University

Bachelor of Science, biotechnology, College of Bioengineering

Work Experience

Jun 2013-Nov 2013, The University of Arizona, international scholars

Jul 2011-present, Institute of food science and technology, CAAS, Associate Professor

Jul 2009–Jul 2011, Feed research institute of CAAS, postdoctor

Research interest

Mainly interested in researches of food microbial biotechnology, especially for industrialization technology and directed evolution of food enzymes. She is also interested in the separating, functional study and biosynthesis of microbial secondary metabolites.

Selected publications

  1. Wang JJ, Wang Y, Hou LZ, Xin FJ, Fan B, Lu C, Zhang LJ, Wang FZ*, Li SY*. Immunomodulatory Protein from Nectria haematococca Induces Apoptosis in Lung Cancer Cells via the P53 Pathway. Int J Mol Sci. 2019, 28;20(21). pii: E5348. doi: 10.3390/ijms20215348.
  2. Xie Y#, Li SY#, Sun L, Liu S, Wang F, Wen B, Sun L, Fang X, Chai Y, Cao H, Jia N, Gu T, Lou X, Xin F*. Fungal Immunomodulatory Protein from Nectria haematococca Suppresses Growth of Human Lung Adenocarcinoma by Inhibiting the PI3K/Akt Pathway. Int J Mol Sci. 2018, 19(11). doi: 10.3390/ijms19113429.
  3. Li SY, Jiang ZH, Sun LC, Liu X, Huang Y, Wang, FZ*, Xin FJ*. Characterization of a New Fungal Immunomodulatory Protein, FIP-dsq2 from Dichomitus squalens. J Biotechnol. 2017, 246:45-51.
  4. Li SY, Jiang ZH, Xu WY, Xie YY, Zhao LM, Tang XM, Wang, FZ*, Xin FJ*. FIP-sch2, a new fungal immunomodulatory protein from Stachybotrys chlorohalonata, suppresses proliferation and migration in lung cancer cells. Appl Microbiol Biol. 2017, 101(8):3227-3235.
  5. Li SY, Zhao LM, Xu WY, Jiang ZH, Kang J, Wang, FZ*, Xin FJ*. Identification and Characterisation of a Novel Protein FIP-sch3 from Stachybotrys chartarum. PLOS ONE. 2016,11(12):e0168436. DOI: 10.1371/journal.pone.0168436.
  6. Li SY, Nie Y, Ding Y, Zhao JH, Tang XM*. Effects of Pure and Mixed Koji Cultures with Saccharomyces cerevisiae on Apple Homogenate Cider Fermentation. J Food Precess Pres. 2015, 39, 2421-2430.
  7. Li SY, Shi LJ, Ding Y, Nie Y, Tang XM*. Identification and functional characterization of a novel fungal immunomodulatory protein from Postia placenta. Food Chem Toxicol. 2015, 78:64-70.
  8. Li SY, Nie Y, Ding Y, Shi L, Tang X*. Recombinant Expression of a Novel Fungal Immunomodulatory Protein with Human Tumor Cell Antiproliferative Activity from Nectria haematococca. Int. J. Mol. Sci. 2014, 15, 17751-17764.
  9. Li SY, Yan Y, Zhou Z, Yu H, Zhan Y, Zhang W, Chen M, Lu W, Ping S, Lin M*. Single amino acid residue changes in subsite -1 of levansucrase from Zymomonas mobilis 10232 strongly influence the enzyme activities and products. Mol Biol Rep (2011) 38(4):2437-2443.
  10. Li SY, Chen M, Li G, Yan YL, Yu HY, Zhan YH, Peng ZX, Wang J, Lin M*. Amino acid substitutions of His296 alter the catalytic properties of Zymomonas mobilis 10232 levansucrase. Acta Biochim Pol. 2008; 55(1):201-206.


Address: No 2, Yuanmingyuan West Rd., Beijing, P.R. China

Tel: +86-10-62810295

Fax: +86-10-62810295

E-mail: lishuying@caas.cn